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Deux nuances importantes ressortent de cette mta-analyse

3 Adherence is the key to maximizing impact: Strong adherence drives strong outcomes

Vera et al., 2024), and SR13800 (Chatterjee et al., 2023

Cai C, et al

Several factors influence DPP-4 activity: Genetics: Polymorphisms in the DPP4 gene affect enzyme expression and activity Metabolic status: Insulin resistance correlates with elevated DPP-4 activity Inflammation: Chronic inflammation increases DPP-4 expression Age: DPP-4 activity tends to increase with aging Diet composition: Certain dietary patterns modulate DPP-4 expression This variability explains why some people maintain better natural GLP-1 levels than others, even with similar L-cell activation strategies